(R)-(-)-3-Pyrrolidinol hydrochloride CAS 104706-47-0 can be used to prepare darfinacine hydrobromide, which is a Chemicalbook selective muscarinic M3 developed by Novartis, Switzerland Receptor antagonist, first listed in Germany in 2005, clinically used to treat overactive bladder such as urinary incontinence, urgency and frequency.
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Product Name |
(R)-(-)-3-Pyrrolidinol hydrochloride |
||
Formula |
C4H10ClNO |
Molecular Weight |
123.58 |
CAS NO. |
104706-47-0 |
Quantity |
500KG |
Items |
Specification |
Results |
Appearance |
Brown Powder |
Conforms |
Assay |
≥99.0% |
99.25% |
CONCLUSION |
The result conform with standard |
Melting point 104-107°C (lit.)
Specific rotation -7.6°(20/D,c=3,5,CH3OH)
Refractive index -7.8°(C=3.5,MeOH)
Storage conditionsInertatmosphere, RoomTemperature
Solubility Solublein DMSO.
MorphologySolid
Color PaleBrown
Optical activity [α]20/D7.6°, c=
(R)-3-Hydroxypyrrolidine hydrochloride can be used to prepare darfinacine hydrobromide, which is a Chemicalbook selective muscarinic M3 receptor antagonist developed by Novartis, Switzerland, 2005 It was first marketed in Germany in 2018 and is clinically used for the treatment of overactive bladder such as urinary incontinence, urgency and frequency of urination.
(R)-3-Hydroxypyrrolidine hydrochloride is a heterocyclic organic compound, which can be used as a pharmaceutical intermediate.