2-Aminonicotinic acid CAS 5345-47-1

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2-Aminonicotinic acid CAS 5345-47-1 Chemical Specification 

2-Aminonicotinic acid CAS 5345-47-1 Chemical Properties

Melting point 295-297°C(dec.)(lit.)
Boiling point 253.51°C (roughestimate)
Density 1.3471 (roughestimate)
Refractive index 1.5100(estimate)
Storage conditions Keepindarkplace, Inertatmosphere, Roomtemperature
Solubility DMSO
Acidity coefficient (pKa) 2.94±0.10 (Predicted)
MorphologyCrystallinePowder
Color Off-whitetolightyellow
water solubility

2-Aminonicotinic acid CAS 5345-47-1 Application

2-Aminonicotinic acid CAS 5345-47-1 is an important pharmaceutical and pesticide intermediate. Traditionally, 3-nitrile pyridine or 3-amidopyridine is used as raw material, by activating the pyridine ring, chlorinating at the 2-position of the pyridine ring and then passing through obtained by hydroxylation. Due to the complex synthesis circuit and low yield, the cost and price are very high.

Organic Synthesis. Sulfathiazole Intermediates