2-Chloro-4-fluorobenzoic acid CAS 2252-51-9
  • 2-Chloro-4-fluorobenzoic acid CAS 2252-51-92-Chloro-4-fluorobenzoic acid CAS 2252-51-9

2-Chloro-4-fluorobenzoic acid CAS 2252-51-9

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2-Chloro-4-fluorobenzoic acid CAS 2252-51-9 Chemical Specification 

Product Name 

 2-Chloro-4-fluorobenzoic acid



Molecular Weight










 white powder






 1.4016  1.4016
Melting point 

 181-183 °C



The result conform with standard

2-Chloro-4-fluorobenzoic acid CAS 2252-51-9 Chemical Properties

Melting point 181-183 ° C (lit.)
Boiling point 271.9 ± 20.0 ° C (predicted)
Density 1.4016 (estimate)
Storage conditions sealedindry, roomtemperature
Solubility 95%ethanol:solid 50mg/ml, clear to very slowly hazy, colorless to very fancy yellow
Acidity coefficient (PKA) 2.90 ± 0.25 (predicted)
Morphology powder or flakes
Color white

2-Chloro-4-fluorobenzoic acid CAS 2252-51-9 Application

2-chloro-4-fluorobenzoic acid is a useful synthetic intermediate. It can be used to prepare arylaminopyrazole benzamide as an oral non steroidal selective glucocorticoid receptor agonist. It can also be used as arginine vasopressin V2 receptor agonist in the synthesis of (4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzozeheptane-5-ethylidene) acetamide derivatives

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