2-Chloro-5-nitropyridine CAS 4548-45-2
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2-Chloro-5-nitropyridine CAS 4548-45-2

2-Chloro-5-nitropyridine CAS 4548-45-2 is a needle-like crystal that precipitates from water. Melting point 108-110 ℃.

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Product Description

Believe Chemical is a leading China 2-Chloro-5-nitropyridine CAS 4548-45-2 manufacturer, supplier and exporter. Adhering to the pursuit of perfect quality of products, so that our 2-Chloro-5-nitropyridine CAS 4548-45-2 have been satisfied by many customers. Shandong Believe Chemical Pte. Ltd. is a high-tech enterprise integrating R &D and sales of chemical technology. 

We are good at the advantages of chemical products in the field. Our products are exported to Europe, the United States, Japan, South Korea, Southeast Asia and other countries and regions. With science and technology as the guide, honesty as the foundation, quality as the life, and relying on the enterprise concept of innovation and development, we sincerely hope to establish exchanges and extensive cooperation with domestic and foreign customers to create prosperity!

2-Chloro-5-nitropyridine CAS 4548-45-2 Chemical Specification 

Product Name




Molecular Weight 










Light yellow to beige Crystalline Powder



99% 99.28%


The result conform with standard

2-Chloro-5-nitropyridine CAS 4548-45-2 Chemical Properties

Melting point 105-108°C(lit.)
Boiling point 256.6±20.0°C(Predicted)
Density 1.6616 (roughestimate)
Refractive index 1.5500 (estimate)
Flash point 158°C
Storage conditions Keepindarkplace, Sealedindry, RoomTemperature acidity coefficient (pKa) -4.22±0.10 (Predicted)

2-Chloro-5-nitropyridine CAS 4548-45-2 Application

A preparation method of utilizing dichlorine monoxide to prepare 2-chloro-5-nitropyridine is to mix 3-nitropyridine and 1-3 times the amount of alkali in molar ratio, 1-2 times the amount of chloride salt and The solvent is mixed evenly, and cooled to -15°C to -10°C at a low temperature; after dissolving 2-3 times the molar ratio of dichloride monoxide in the solvent, it is dropped into the reaction mixture under full stirring, and maintained at -10°C. To 0 ° C, the dropwise addition was completed for 2 hours, the temperature was raised to room temperature and continued to stir for 2 hours until the reaction of the raw material 3-nitropyridine was complete, the reactant was poured into ice water, the organic layer was separated, the organic layer was collected, and the mass concentration of the organic layer was Wash with 5% hydrochloric acid once, wash with water once, dry with anhydrous magnesium sulfate, and evaporate the organic solvent under reduced pressure to obtain 2-chloro-5-nitropyridine.

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