2-Methoxy-5-nitropyridine CAS 5446-92-4
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2-Methoxy-5-nitropyridine CAS 5446-92-4

2-Methoxy-5-nitropyridine CAS 5446-92-4 is obtained by etherification of 2-chloro-5-nitropyridine. Sodium methoxide was added dropwise to the mixture of 2-chloro-5-nitropyridine and methanol under stirring, and crystals were precipitated in crushed ice after adding sulfur for 1 h. Filter, dry, and recrystallize with methanol to obtain the finished product. The yield was 92%.

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Product Description

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We are good at the advantages of chemical products in the field. Our products are exported to Europe, the United States, Japan, South Korea, Southeast Asia and other countries and regions. With science and technology as the guide, honesty as the foundation, quality as the life, and relying on the enterprise concept of innovation and development, we sincerely hope to establish exchanges and extensive cooperation with domestic and foreign customers to create prosperity!

2-Methoxy-5-nitropyridine CAS 5446-92-4 Chemical Specification 

Product Name




Molecular Weight 










 Clear colorless to yellow Liquid






The result conform with standard

2-Methoxy-5-nitropyridine CAS 5446-92-4 Chemical Properties

Melting point 104-108°C (lit.)
Boiling point 277.46°C (roughestimate)
Density 0.45
Refractive index 1.5100(estimate)
Flash point 130°C
Storage ConditionsSealedindry,ChemicalbookRoomTemperatureForm Liquid
Acidity coefficient (pKa)-0?+-.0.10(Predicted)
water solubility insoluble

2-Methoxy-5-nitropyridine CAS 5446-92-4 Application

for organic synthesis. The product is reduced to obtain 5-amino-2-methoxypyridine, which is the intermediate of the drug. For example, it is used to produce the antimalarial rescue drug pyronaridine.
Used as a pharmaceutical intermediate

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