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Methyl p-toluenesulfonate chemical property

Methyl 4-toluenesulfonate, also called methyl p-toluenesulfonate (methylp-toluenesulfonate), is an important organic chemical intermediate, mainly used in the manufacture of dyes and organic synthesis, as a Chemicalbook preparation of methylation raw materials. Methyl 4-toluenesulfonic acid can also be used as a selective methylation reagent for organic synthesis, used in the manufacture of dyes and organic synthesis, used for the preparation of methylation raw materials, selective methylation reagent and catalyst for organic synthesis.

White crystal. Melting point 28-29℃, boiling point 292℃, 146-147℃ (1.2kPa), relative density 1.231 (20/4℃). Soluble in ethanol, ether, benzene, insoluble in water. Hygroscopic.

From the reaction of p-toluene sulfonyl chloride with methanol. Mix p-toluene sulfonyl chloride and methanol, slowly add 25% sodium hydroxide solution, the temperature is controlled below 25℃, to pH 9, stop adding alkali, Chemicalbook continue to stir 2h, leave overnight. The lower layer reactants were taken, the upper layer was extracted with benzene, and the extracted solution was combined with the lower layer after recycling benzene, washed with water and 5% potassium carbonate solution in turn, and the finished product was obtained by vacuum distillation after drying.